A 2018 study claiming fatty acid supplements protected eye nerve cells in mice with MS-like disease has been retracted by the journal Nutrients and is no longer considered reliable scientific evidence. According to Gram Research analysis, retracted studies should not be used to guide health decisions. People with MS interested in supplements should consult their doctor about treatments based on current, valid research instead.

A 2018 study published in Nutrients that suggested fatty acid supplements could help protect eye cells in multiple sclerosis has been officially retracted by the journal. The retraction means the research no longer stands as reliable scientific evidence. This is an important reminder that scientific findings sometimes need to be withdrawn when problems are discovered. Readers who may have seen this study should know it’s no longer considered valid research, and people with MS should continue following their doctor’s advice about supplements rather than relying on this particular study.

Key Statistics

A 2018 study published in Nutrients claiming fatty acid supplements reduced inflammation and protected eye nerve cells in mice with multiple sclerosis-like disease has been officially retracted by the journal, meaning the findings are no longer considered scientifically valid.

The retraction of this animal study demonstrates why peer review and scientific accountability matter—researchers and healthcare providers must rely only on studies that have not been withdrawn due to methodological or other serious concerns.

The Quick Take

  • What they studied: Whether fatty acid supplements could reduce inflammation and protect nerve cells in the eyes of mice with a disease similar to multiple sclerosis
  • Who participated: Laboratory mice with an experimental autoimmune disease designed to mimic multiple sclerosis; no human participants were involved
  • Key finding: The original study claimed fatty acids reduced inflammation and protected eye nerve cells, but this research has been retracted and is no longer considered reliable
  • What it means for you: If you have MS or were considering fatty acid supplements based on this study, you should not rely on these findings. Talk to your doctor about supplement safety and effectiveness instead

The Research Details

The original study was conducted in laboratory mice that had been given a disease similar to multiple sclerosis. Researchers gave some mice fatty acid supplements and compared them to mice that didn’t receive the supplements. They then examined the mice’s eyes to see if the supplements protected nerve cells from damage caused by inflammation.

This type of animal study is often an early step in research. Scientists use animal models to test ideas before they can be studied in humans. However, results in mice don’t always translate to humans, which is why animal studies need careful interpretation.

Animal studies can help scientists understand how diseases work and test whether treatments might be safe and effective. However, this particular study’s retraction means the scientific community found problems serious enough that the results can no longer be trusted. This is why peer review and the ability to retract flawed studies is important—it protects people from following bad advice.

This study has been retracted by the journal Nutrients, meaning the editors determined there were significant problems with the research that made it unreliable. The specific reasons for retraction were not detailed in the available information, but retraction is a serious action taken only when major issues are discovered. Readers should not cite or rely on this study for any health decisions.

What the Results Show

The original study reported that mice receiving fatty acid supplements showed reduced inflammation markers in their eyes and better protection of nerve cells compared to control mice. However, these findings are no longer considered valid because the article has been retracted.

Retraction means the journal’s editors and peer reviewers determined the study had problems significant enough that the results cannot be trusted. This could involve issues with the methodology, data analysis, or other scientific concerns.

When a study is retracted, it’s removed from the scientific record as reliable evidence. Other researchers and healthcare providers should not use it to make decisions about treatments or recommendations.

No secondary findings are relevant to report, as the entire study has been retracted and withdrawn from scientific literature.

While other research has explored the role of fatty acids in inflammation and eye health, this particular study cannot be compared to or built upon because it is no longer considered valid. Researchers interested in this topic would need to rely on other peer-reviewed studies that have not been retracted.

The most significant limitation is that this study has been retracted and is no longer considered reliable scientific evidence. Additionally, as an animal study in mice, any findings would have needed extensive additional research in humans before being applicable to people with MS. The retraction prevents any further discussion of the study’s specific methodological limitations.

The Bottom Line

Do not use this retracted study as a basis for taking fatty acid supplements for MS-related eye problems. If you have multiple sclerosis and are interested in supplements, discuss options with your neurologist or healthcare provider who can recommend treatments based on current, reliable evidence. Confidence level: High—this recommendation is based on the study’s retraction status.

People with multiple sclerosis who may have read about this study, healthcare providers who need current evidence, and anyone considering fatty acid supplements for eye health should be aware this study is no longer valid. Researchers studying MS and eye health should not cite this retracted work.

Not applicable, as this study’s findings are no longer considered reliable and should not be used to guide treatment decisions.

Frequently Asked Questions

Should I take fatty acid supplements if I have multiple sclerosis based on recent research?

A 2018 study suggesting fatty acids help MS eye health was retracted and is no longer valid. Discuss any supplements with your neurologist, who can recommend treatments based on current, reliable evidence rather than retracted studies.

What does it mean when a scientific study is retracted?

Retraction means the journal determined serious problems with the research made it unreliable. The study is removed from scientific literature and should not be used to guide health decisions or future research.

Can I still trust research about fatty acids and inflammation?

Yes, but only studies that have not been retracted. Look for peer-reviewed research published in reputable journals. Ask your doctor which studies provide the best current evidence for your specific health situation.

Why would researchers retract a study after it was already published?

Problems discovered after publication—such as flawed methodology, data errors, or ethical concerns—can lead to retraction. This process protects public health by removing unreliable information from the scientific record.

Want to Apply This Research?

  • If using supplements, track any changes in vision or eye symptoms in your health app, but base supplement decisions on current medical advice from your doctor, not on retracted studies
  • Remove this study from any research notes or supplement decisions you may have made based on it; consult your healthcare provider for evidence-based supplement recommendations
  • Continue regular eye exams and MS monitoring with your healthcare team; do not adjust treatments based on retracted research

This study has been retracted by the journal Nutrients and is no longer considered valid scientific evidence. Do not use this research to make health decisions. If you have multiple sclerosis or are considering dietary supplements, consult with your healthcare provider or neurologist for evidence-based recommendations. This article is for informational purposes only and does not constitute medical advice. Always discuss supplement use with your doctor before starting any new regimen.

This research translation is published by Gram Research, the science division of Gram, an AI-powered nutrition tracking app.

Source: RETRACTED: Dal Monte et al. Fatty Acids Dietary Supplements Exert Anti-Inflammatory Action and Limit Ganglion Cell Degeneration in the Retina of the EAE Mouse Model of Multiple Sclerosis. Nutrients 2018, 10, 325.Nutrients (2026). PubMed 42407061 | DOI