Heart disease risk in Korea has nearly doubled over 20 years, with 10-year cardiovascular risk increasing from 4.6% in 2001 to 7.9% in 2021, according to Gram Research analysis of national health data. Rising blood sugar levels and increased blood pressure medication use are the primary drivers, though declining smoking rates and higher good cholesterol have provided some protection. The 30-year risk climbed even more dramatically from 15.8% to 22.9%, signaling that prevention efforts must intensify.

A major study tracking Korean adults over 20 years found that the risk of developing heart disease has increased significantly. Researchers used a special calculator called the PREVENT equation to measure how likely people are to have heart problems in the next 10 and 30 years. The good news: some protective factors like higher good cholesterol and fewer smokers helped slow the increase. The concerning trend: rising blood sugar levels and more people taking blood pressure medications suggest Koreans are facing greater cardiovascular challenges as their country modernizes.

Key Statistics

A 20-year cross-sectional analysis of Korean adults found that estimated 10-year cardiovascular disease risk nearly doubled from 4.6% in 2001 to 7.9% in 2021, based on data from the Korea National Health and Nutrition Examination Survey.

According to research reviewed by Gram, 30-year cardiovascular disease risk in Korea increased from 15.8% to 22.9% between 2001 and 2021, driven primarily by worsening blood glucose control (rising from 97 to 103 mg/dL).

A 2026 study of Korean cardiovascular trends found that male smoking rates declined from 47.9% in 2001 to 28.9% in 2021, providing a protective effect that partially offset increased risk from other factors.

Korean adults showed increased high-density lipoprotein (good) cholesterol levels over the 20-year period, which helped mitigate what would have been an even steeper rise in estimated cardiovascular disease risk.

The Quick Take

  • What they studied: How heart disease risk has changed in Korean adults from 2001 to 2021, and what factors are driving these changes
  • Who participated: Adults aged 30 and older from Korea who participated in national health surveys over a 20-year period, representing the general Korean population
  • Key finding: The estimated 10-year risk of heart disease nearly doubled from 4.6% in 2001 to 7.9% in 2021, while 30-year risk increased from 15.8% to 22.9%
  • What it means for you: If you’re Korean or of Korean descent, your personal heart disease risk may be higher than it was two decades ago. This suggests the need for more aggressive prevention through diet, exercise, and regular health screenings—especially if you have high blood sugar or high blood pressure

The Research Details

Researchers analyzed data from Korea’s National Health and Nutrition Examination Survey (KNHANES), which is like a giant health checkup program that tracks thousands of Koreans over time. They looked at information collected between 2001 and 2021—a 20-year window. For each person, they measured things like blood pressure, cholesterol levels, blood sugar, smoking status, and other health markers.

They then used a special mathematical tool called the PREVENT equation to calculate each person’s risk of developing heart disease over the next 10 years and the next 30 years. This equation was designed to work fairly across different racial and ethnic groups, making it useful for studying Korean populations. By comparing these risk calculations across the two decades, they could see whether Koreans were becoming more or less likely to develop heart problems.

This approach is important because it shows real-world trends in a large population rather than just looking at individual cases. By tracking the same measurements over 20 years, researchers can identify which factors are getting better or worse and understand how economic development and lifestyle changes affect heart health. The PREVENT equation is relatively new for Asian populations, so this study helps validate whether it works well for Koreans.

This study used nationally representative data, meaning the results likely reflect the broader Korean population rather than just one hospital or clinic. The 20-year timespan is substantial and captures major societal changes. However, the study is cross-sectional, which means it shows snapshots in time rather than following the same individuals throughout the entire period. This limits our ability to say definitively that individual people’s risk increased—we can only say the population’s average risk went up.

What the Results Show

The most striking finding is the substantial increase in estimated cardiovascular disease risk over two decades. The 10-year risk—the chance of having a heart attack or stroke in the next decade—nearly doubled from 4.6% to 7.9%. This means that if you took 100 Korean adults in 2001, about 4-5 would be expected to have a cardiovascular event within 10 years. By 2021, that number had grown to nearly 8 out of 100.

The 30-year risk showed an even more dramatic increase, climbing from 15.8% to 22.9%. This suggests that as Koreans age, their cumulative risk of developing heart disease has grown substantially. These increases occurred despite some positive trends, indicating that negative factors outweighed protective ones.

The researchers identified blood sugar control as a major driver of increased risk. Average blood glucose levels rose from 97 mg/dL in 2001 to 103 mg/dL in 2021—a meaningful increase that suggests more people are developing prediabetes or diabetes. Additionally, more people were taking blood pressure medications in 2021 compared to 2001, which could indicate either better detection of high blood pressure or worsening blood pressure control in the population.

Not all trends were negative. High-density lipoprotein (HDL) cholesterol—the ‘good’ kind that protects your heart—increased over the 20-year period. This protective factor likely prevented the risk increase from being even steeper. Additionally, male smoking rates dropped dramatically from 47.9% in 2001 to 28.9% in 2021. Since smoking is a major heart disease risk factor, this decline in smoking helped offset some of the increased risk from worsening blood sugar control. These positive trends suggest that public health campaigns against smoking and improvements in cholesterol management have had real benefits.

This study is among the first to apply the PREVENT equation to long-term Korean population data. Previous research in other Asian countries has shown similar patterns of increasing cardiovascular risk with economic development and urbanization. The findings align with global trends showing that as countries become wealthier and more developed, lifestyle-related risk factors like obesity, diabetes, and sedentary behavior tend to increase. However, the magnitude of increase in Korea is notable and suggests that prevention efforts need to be strengthened.

The study has several important limitations. First, it’s cross-sectional, meaning researchers compared different groups of people at different time points rather than following the same individuals over 20 years. This makes it harder to prove that individual risk increased versus the population composition changing. Second, the PREVENT equation is relatively new for Asian populations, so we don’t have as much validation data as we do for other groups. Third, the study doesn’t explain why blood sugar control worsened—it could be due to increased obesity, dietary changes, reduced physical activity, or other factors not fully explored. Finally, the study is limited to Korea, so results may not apply to other Asian countries or populations.

The Bottom Line

Based on this research, Korean adults should prioritize cardiovascular prevention through: (1) Regular blood sugar monitoring and maintaining healthy glucose levels through diet and exercise—this is the strongest modifiable risk factor identified; (2) Blood pressure management through medication if needed and lifestyle changes; (3) Maintaining or increasing HDL cholesterol through regular aerobic exercise and healthy fats; (4) Avoiding smoking or quitting if you currently smoke. These recommendations have high confidence because they target the specific risk factors shown to be worsening in this study.

This research is most relevant for Korean adults aged 30 and older, particularly those with family histories of heart disease, high blood pressure, or diabetes. It’s also important for healthcare providers and public health officials in Korea and other Asian countries undergoing similar economic development. People of Korean descent living elsewhere should also consider these findings relevant to their own risk assessment. However, the findings don’t necessarily apply to younger adults or to populations with very different genetic backgrounds or lifestyles.

Cardiovascular disease develops over years and decades, not weeks or months. If you make lifestyle changes today based on these findings, you might see improvements in blood sugar and blood pressure within 3-6 months. However, meaningful reductions in actual heart disease risk typically take 1-2 years of consistent healthy behaviors. The 30-year risk estimates in this study remind us that prevention is a long-term commitment.

Frequently Asked Questions

Has heart disease risk increased in Korea over the past 20 years?

Yes. Estimated 10-year cardiovascular risk nearly doubled from 4.6% to 7.9% between 2001 and 2021, while 30-year risk increased from 15.8% to 22.9%. Rising blood sugar levels and increased blood pressure medication use are primary drivers of this increase.

What is causing higher heart disease risk in Korean adults?

Worsening blood glucose control is the main factor—average glucose rose from 97 to 103 mg/dL. More people are also taking blood pressure medications, suggesting either better detection or worse control of hypertension. These negative trends outweighed protective factors like declining smoking rates.

Yes. Male smoking rates dropped significantly from 47.9% to 28.9%, and high-density lipoprotein (good) cholesterol levels increased. These improvements helped prevent the risk increase from being even steeper, showing that some public health efforts are working.

What should I do if I’m Korean and concerned about heart disease risk?

Focus on blood sugar control through diet and exercise, manage blood pressure, maintain healthy cholesterol, and avoid smoking. Regular health screenings are important. These lifestyle changes address the specific risk factors shown to be worsening in Korean populations over the past two decades.

Does this study apply to Korean people living outside Korea?

The findings are likely relevant to people of Korean descent, as genetic factors and shared cultural dietary patterns may create similar risk profiles. However, local lifestyle factors and healthcare access also influence individual risk, so consult your doctor about your personal cardiovascular risk.

Want to Apply This Research?

  • Track fasting blood glucose weekly and blood pressure daily. Set a goal to keep fasting glucose below 100 mg/dL (the 2001 Korean average) and blood pressure below 130/80 mmHg. Log these measurements in your health app to visualize trends over months.
  • Use the app to set reminders for aerobic exercise at least 150 minutes per week, which helps both blood sugar control and HDL cholesterol. Create a meal plan focused on reducing refined carbohydrates and increasing fiber to address the rising blood glucose trend identified in the study.
  • Establish a quarterly review where you compare your blood glucose and blood pressure trends to the Korean population averages mentioned in this study (103 mg/dL and increasing medication use). This provides concrete benchmarks for whether your personal risk is improving or worsening relative to population trends.

This research provides population-level insights about cardiovascular disease risk trends in Korea and should not be used for individual medical diagnosis or treatment decisions. The PREVENT equation is a risk estimation tool, not a diagnostic test. Individual cardiovascular risk depends on many factors beyond those measured in this study. If you have concerns about your heart disease risk, consult with your healthcare provider who can perform a comprehensive assessment, consider your complete medical history, and recommend personalized prevention or treatment strategies. This article is for educational purposes and does not constitute medical advice.

This research translation is published by Gram Research, the science division of Gram, an AI-powered nutrition tracking app.

Source: Ten- and thirty-year cardiovascular disease risks using PREVENT equation in Koreans from 2001 to 2021.International journal of epidemiology (2026). PubMed 42470135 | DOI