A 2026 research study found that adding 1.5% microencapsulated fermented catfish waste extract to broiler chicken feed improved energy utilization and reduced harmful Staphylococcus aureus bacteria by 16.6%, performing as well as standard antibiotic growth promoters. According to Gram Research analysis, this fermented fish waste additive could help farmers raise healthier chickens without antibiotics while converting food-processing waste into a valuable product.

Researchers tested a new feed additive made from fermented catfish waste to see if it could help chickens grow better and stay healthier. According to Gram Research analysis, adding this special ingredient to chicken feed improved how well the birds used energy from their food and helped their digestive systems work better. The best results came when farmers added 1.5% of this additive to the feed. This discovery is exciting because it could help farmers raise healthier chickens without using antibiotics, while also finding a useful purpose for fish-processing waste that would normally be thrown away.

Key Statistics

A 2026 research article found that 1.5% microencapsulated fermented catfish waste extract reduced Staphylococcus aureus counts by 16.6% in broiler chickens compared to control feed, matching the effectiveness of zinc bacitracin antibiotic growth promoters.

Research published in Food Science & Nutrition in 2026 showed that fermented catfish waste additive significantly improved apparent metabolizable energy (p = 0.003) and nitrogen retention in broiler chickens, with optimal results at 1.5% dietary inclusion.

A 2026 study demonstrated that microencapsulated fermented catfish waste extract enhanced digestive enzyme activity in broiler chickens, improving nutrient digestibility without negatively affecting beneficial gut bacteria populations.

The Quick Take

  • What they studied: Whether a new feed additive made from fermented catfish waste could help broiler chickens (chickens raised for meat) grow better, digest food more efficiently, and maintain healthier gut bacteria without using antibiotics.
  • Who participated: Broiler chickens divided into six groups receiving different feed treatments, including a control group, a group given standard antibiotic growth promoter, and four groups receiving increasing amounts of the fermented catfish waste additive.
  • Key finding: Adding 1.5% microencapsulated fermented catfish waste extract to chicken feed improved energy utilization and reduced harmful bacteria like Staphylococcus aureus by 16.6% compared to the control group, matching or exceeding the benefits of antibiotic growth promoters.
  • What it means for you: If you eat chicken, this research suggests farmers may soon have a natural, antibiotic-free way to raise healthier birds while reducing food waste. However, this is early-stage research in animals, and more testing would be needed before widespread farm use.

The Research Details

Scientists conducted a controlled experiment with broiler chickens divided into six groups. One group ate regular feed (the control), another group received feed with a standard antibiotic growth promoter used in farming, and four groups received feed containing increasing amounts of the new fermented catfish waste additive—0.5%, 1.0%, 1.5%, and 2.0%. At 35 days old, the researchers measured how efficiently the chickens converted feed into body weight, tested their digestive enzyme activity, and analyzed the types and amounts of bacteria living in their intestines.

The fermented catfish waste was specially processed using microencapsulation, which is a technique that wraps tiny particles in a protective coating. This coating helps the beneficial compounds survive the chicken’s digestive system and reach the intestines where they’re most needed. The researchers measured several important outcomes: apparent metabolizable energy (how much usable energy the chickens got from their food), nutrient digestibility (how well they absorbed nutrients), digestive enzyme activity (how well their digestive system worked), and intestinal bacteria populations (the types and amounts of microbes in their guts).

This approach represents a circular economy strategy, meaning it takes a waste product from fish processing and converts it into something valuable for animal agriculture, reducing environmental impact while improving animal health.

This research design is important because it tests a real-world solution to a significant farming problem: reducing antibiotic use in animal agriculture. Overuse of antibiotics in farming has contributed to antibiotic-resistant bacteria, a major public health concern. By testing a natural alternative that uses food-processing waste, the study addresses both animal health and environmental sustainability. The specific measurements of digestive function and gut bacteria help explain how the additive works, not just whether it works.

The study used a completely randomized design, which is a strong research approach that helps eliminate bias. The researchers measured multiple endpoints (energy use, nutrient absorption, enzyme activity, and bacterial populations) rather than relying on a single outcome, which strengthens confidence in the findings. The study was published in a peer-reviewed journal, meaning other experts reviewed the work before publication. However, the specific sample size wasn’t clearly stated in the abstract, and the study was conducted only in chickens, so results may not apply to other animals or to human nutrition.

What the Results Show

The fermented catfish waste additive significantly improved how efficiently chickens used energy from their feed. Apparent metabolizable energy (AME) and adjusted metabolizable energy (AMEn)—measures of how much usable energy chickens got from food—both improved with the additive (p = 0.003 and p = 0.007, respectively). Nitrogen retention, which indicates how well chickens absorbed and used protein, also improved significantly (p < 0.05).

The most impressive results came at the 1.5% inclusion level. At this dose, the additive reduced Staphylococcus aureus (a harmful bacteria) by 16.6% compared to chickens eating regular feed without the additive. This reduction was statistically significant (p = 0.003), meaning it wasn’t due to chance. Importantly, the 1.5% dose performed as well as or better than the standard antibiotic growth promoter used as a comparison.

Digestive enzyme activity—which measures how well the chickens’ digestive systems were functioning—also improved with the additive. These enzymes are crucial for breaking down food and absorbing nutrients. The improvements in enzyme activity help explain why the chickens showed better energy utilization and nutrient absorption.

While the additive successfully reduced Staphylococcus aureus, it did not significantly affect total aerobic bacteria counts or Escherichia coli (E. coli) levels in the intestines. This is actually a positive finding because it suggests the additive selectively reduces harmful bacteria while preserving the overall bacterial community structure, which is important for gut health. The dose-response pattern showed that 1.5% was optimal; higher doses (2.0%) didn’t provide additional benefits, suggesting there’s a sweet spot for effectiveness.

This research builds on growing interest in replacing antibiotic growth promoters with natural alternatives in animal agriculture. Previous studies have explored fermented feed ingredients and fish-based products, but this appears to be among the first to specifically test microencapsulated fermented catfish waste. The results are encouraging because they show the additive performs comparably to zinc bacitracin, a widely-used antibiotic growth promoter, suggesting it could be a viable replacement. The circular economy approach—converting processing waste into a valuable feed ingredient—aligns with recent trends in sustainable agriculture.

The study has several important limitations. First, the specific number of chickens used wasn’t clearly stated in the abstract, making it difficult to assess statistical power. Second, the research was conducted only in broiler chickens, so results may not apply to other poultry species or other animals. Third, the study measured outcomes at only one time point (day 35), so we don’t know if benefits persist longer or if there are any long-term effects. Fourth, while the additive reduced one harmful bacteria (Staphylococcus aureus), it didn’t affect other common pathogens like E. coli, so its protective benefits may be limited. Finally, this is a laboratory-controlled study; real-world farm conditions might produce different results.

The Bottom Line

Based on this research, 1.5% microencapsulated fermented catfish waste extract shows promise as a feed additive for broiler chickens, with moderate to strong evidence supporting its use as a potential replacement for antibiotic growth promoters. However, recommendations should be considered preliminary because this is early-stage research. Farmers interested in using this additive should conduct their own trials under their specific conditions and consult with veterinarians and nutritionists. The additive appears safe at tested levels, but long-term safety data in commercial settings would strengthen confidence.

Poultry farmers and the agricultural industry should pay attention to this research, as it offers a potential solution to reducing antibiotic use while improving chicken health and utilizing food-processing waste. Consumers concerned about antibiotic use in food production may find this development encouraging. Environmental advocates should appreciate the circular economy approach. However, consumers shouldn’t expect immediate changes, as this research needs to be validated in commercial farm settings before widespread adoption. People with fish allergies or sensitivities should be aware this additive is fish-derived, though the microencapsulation may reduce allergen concerns.

If this additive were adopted by farms, improvements in chicken health and growth efficiency would likely be visible within the standard 35-day broiler production cycle. However, regulatory approval and commercial production of the additive would likely take 1-3 years. Widespread farm adoption could take 3-5 years or longer, depending on cost, availability, and regulatory requirements.

Frequently Asked Questions

Can fermented fish waste replace antibiotics in chicken farming?

A 2026 study found that 1.5% microencapsulated fermented catfish waste extract reduced harmful bacteria and improved chicken growth as effectively as antibiotic growth promoters. However, more research in commercial farm settings is needed before widespread replacement.

What percentage of fish waste additive works best for chickens?

Research shows 1.5% microencapsulated fermented catfish waste extract provided the most consistent improvements in energy utilization, nutrient absorption, and harmful bacteria reduction. Higher doses (2.0%) didn’t provide additional benefits.

Does fermented fish waste improve chicken digestion?

Yes, the 2026 study found the additive significantly improved digestive enzyme activity and nutrient digestibility in broiler chickens, helping them convert feed into body weight more efficiently.

Is fermented catfish waste safe for chickens to eat?

The study tested doses up to 2.0% without reporting safety concerns, and the 1.5% dose performed optimally. However, long-term safety data in commercial farm conditions would provide additional assurance.

How does microencapsulation help the fish waste additive work?

Microencapsulation wraps the additive in a protective coating that helps beneficial compounds survive the chicken’s digestive system and reach the intestines where they’re most effective for improving digestion and reducing harmful bacteria.

Want to Apply This Research?

  • For farmers using this additive: Track weekly feed conversion ratio (pounds of feed per pound of weight gain), monitor flock health indicators (mortality rate, disease incidence), and measure final body weight at processing. Compare these metrics to previous flocks raised without the additive.
  • Farmers could implement a trial protocol: divide a flock into two groups—one receiving standard feed and one receiving feed with 1.5% microencapsulated fermented catfish waste extract. Track feed consumption, weight gain, and health observations daily using the app, then compare results at the end of the production cycle.
  • Establish a baseline by tracking current performance metrics for 2-3 flocks, then introduce the additive and track the same metrics for 2-3 subsequent flocks. Use the app to create side-by-side comparisons of feed efficiency, growth rates, and health outcomes. Document any changes in feed costs and overall profitability to assess economic viability.

This research describes results from a controlled laboratory study in broiler chickens and should not be considered a recommendation for immediate farm use. The microencapsulated fermented catfish waste extract has not been approved by regulatory agencies such as the FDA for use in animal feed in all jurisdictions. Farmers considering this additive should consult with veterinarians, animal nutritionists, and local agricultural extension services before implementation. Results from controlled studies may not replicate in commercial farm settings with different environmental conditions, management practices, or chicken genetics. This additive is derived from fish and may pose concerns for individuals with fish allergies, though the processing may reduce allergen content. Long-term safety and efficacy data in commercial production are limited. Always follow local regulations regarding feed additives and antibiotic alternatives.

This research translation is published by Gram Research, the science division of Gram, an AI-powered nutrition tracking app.

Source: Effect of Microencapsulated Fermented Catfish Waste Extract on Apparent Metabolizable Energy, Nutrient Digestibility, Digestive Enzyme Activity, and Intestinal Microbiota of Broiler Chickens.Food science & nutrition (2026). PubMed 42282440 | DOI