Nutrition supplements for older adults appear to improve health outcomes and either save money or cost very little extra, according to a 2026 systematic review of 12 studies published in Value in Health. Seven studies found supplements saved up to $1,988 per person by reducing hospital visits, while nine studies showed improved health outcomes. However, most studies only tracked results for 6 months or less, so longer-term benefits remain unclear.

Researchers reviewed 12 studies examining whether nutrition drinks and supplements help older adults stay healthy and save money. According to Gram Research analysis, most studies found that these supplements improved health outcomes and either saved money or cost very little extra. However, the studies looked at short-term results (mostly 6 months or less), so we don’t yet know if the benefits last longer. The research suggests nutrition supplements can be helpful for older adults, but doctors need more long-term studies to understand the full picture of their value.

Key Statistics

A 2026 systematic review of 12 studies found that seven nutrition supplement interventions in older adults saved money (up to $1,988 per person) primarily through reduced healthcare resource utilization, while five studies reported modest cost increases.

According to a 2026 systematic review analyzing 12 health economic evaluations, nine studies reported favorable health outcomes in older adults receiving oral nutrition supplements, with most studies conducted over time horizons of 6 months or less.

A 2026 systematic review of 12 studies found that 11 out of 12 nutrition supplement evaluations included both intervention costs and healthcare service costs, providing a complete economic picture for older adults.

Research reviewed by Gram found that in a 2026 systematic review of 12 studies, eight studies compared nutrition supplements to usual care using trial-based designs, representing the strongest evidence for real-world effectiveness in older adults.

The Quick Take

  • What they studied: Whether oral nutrition supplements (like Ensure or Boost) help older adults get healthier and whether they’re worth the cost
  • Who participated: 12 different research studies involving older adults with an average age of 60 or older, conducted between 2014 and 2024 in hospitals and community settings
  • Key finding: Seven out of 12 studies found that nutrition supplements saved money (up to $1,988 per person) by reducing hospital visits and doctor appointments, while five studies found they cost a bit more. Nine studies showed the supplements improved health outcomes.
  • What it means for you: Nutrition supplements appear to help older adults feel better with minimal extra cost, but most studies only tracked results for 6 months or less. Talk to your doctor about whether supplements make sense for your situation, especially if you’re struggling to eat enough regular food.

The Research Details

Researchers searched six major medical databases for all studies published between 2014 and 2024 that looked at the costs and health benefits of oral nutrition supplements in older adults. They found 1,459 studies initially, but only 12 met their strict criteria for quality and relevance. These 12 studies used different approaches: some compared supplement costs to regular care, others looked at whether supplements prevented hospital visits, and some calculated the cost per quality year of life gained.

The studies took place in different settings—hospitals, nursing homes, and community clinics—and used different comparison groups. Most studies (8 out of 12) were based on actual clinical trials where some people got supplements and others didn’t. The researchers carefully checked each study’s quality using a standard checklist to make sure the findings were reliable.

This systematic review approach is important because it combines results from many different studies to see the big picture. Individual studies can be misleading because they might use different methods or study different types of older adults. By reviewing all the high-quality studies together, researchers can give doctors and patients better information about whether nutrition supplements are actually worth the cost and effort.

The researchers used strict methods to find and evaluate studies, including registering their plan ahead of time (PROSPERO registration) to prevent bias. They used two quality checklists to assess each study’s reliability. However, the 12 studies they found were quite different from each other in terms of methods, settings, and what they measured, which makes it harder to draw firm conclusions. Most studies were short-term (10 out of 12 tracked results for 6 months or less), so we don’t know if benefits last longer.

What the Results Show

Seven of the 12 studies found that nutrition supplements saved money overall, with savings ranging up to $1,988 per person. These savings came mainly from fewer hospital visits and doctor appointments. Five studies found that supplements cost more money, though the extra cost was modest (as little as $356 per person). The difference in results depended on the study setting and which older adults were studied.

Nine studies reported that older adults who received supplements had better health outcomes—they felt better, had fewer complications, or recovered faster from illness. Three studies found mixed results, meaning supplements helped in some ways but not others. Overall, the studies concluded that supplements were either cost-effective (meaning the health benefits justified the cost) or actually saved money.

Most studies (11 out of 12) included both the cost of the supplements themselves and the cost of healthcare services like doctor visits and hospital stays. This gave a complete picture of the total cost. Eight studies compared supplements to usual care (what doctors normally do), which is the most practical comparison for real-world use. Most studies (8 out of 12) were based on actual clinical trials, which is a strong research design.

This review updates and expands on earlier research about nutrition supplements in older adults. Previous studies suggested supplements might help, but this systematic review confirms that most recent studies (2014-2024) show benefits with reasonable costs. The findings align with the growing recognition that malnutrition is a serious problem in older adults that can lead to hospital visits and poor health outcomes.

The biggest limitation is that most studies only tracked results for 6 months or less, so we don’t know if benefits continue over years. The studies were very different from each other—different types of older adults, different settings, different supplements, and different ways of measuring success—which makes it hard to combine the results. Some studies were small or had other quality issues. We also don’t know how well these results apply to different countries or healthcare systems, since most studies were from specific regions.

The Bottom Line

For older adults who aren’t eating enough regular food or who are malnourished, nutrition supplements appear to be helpful and cost-effective (moderate confidence). They seem to improve health outcomes and either save money or add minimal cost. However, supplements should complement, not replace, regular food whenever possible. Discuss with your doctor whether supplements are right for you, especially if you have specific health conditions or take medications.

Older adults (60+) who struggle to eat enough, have recently been hospitalized, are recovering from surgery, or have conditions that affect nutrition should consider discussing supplements with their doctor. Family members and caregivers of older adults should also pay attention to these findings. Healthcare providers and hospital administrators making decisions about nutrition programs should review this evidence. People with no nutrition problems don’t need supplements.

Most studies showed improvements within weeks to months. However, we don’t have good evidence about what happens after 6 months, so it’s unclear if benefits continue long-term or if supplements can be stopped after a certain period. Talk to your doctor about realistic expectations for your specific situation.

Frequently Asked Questions

Are nutrition drinks like Ensure actually worth the cost for older adults?

Research shows nutrition supplements are generally worth the cost. Seven of 12 studies found they saved money (up to $1,988 per person) by reducing hospital visits, while nine studies showed improved health outcomes. However, most studies only tracked results for 6 months, so long-term value is unclear.

Do nutrition supplements really help older people feel better?

Nine out of 12 studies found that older adults receiving nutrition supplements had better health outcomes. Benefits included faster recovery, fewer complications, and improved overall wellness. Results were strongest in people who weren’t eating enough regular food.

How long does it take to see benefits from nutrition supplements?

Most studies showed improvements within weeks to months. However, the research only tracked results for 6 months or less in 10 out of 12 studies, so we don’t know if benefits continue longer. Ask your doctor about realistic timelines for your situation.

Can nutrition supplements replace regular food for older adults?

No. Supplements should complement regular food, not replace it. They’re most helpful for older adults who struggle to eat enough or have specific nutrition gaps. Regular food provides benefits supplements cannot, including fiber, variety, and social eating experiences.

Who should actually use nutrition supplements?

Older adults (60+) who aren’t eating enough, recently had surgery or hospitalization, or have conditions affecting nutrition benefit most. People with no nutrition problems don’t need supplements. Always discuss with your doctor before starting supplements, especially if you take medications.

Want to Apply This Research?

  • Track daily protein and calorie intake using the app’s food logging feature, comparing intake on days with and without supplements. Record weekly energy levels, appetite, and any changes in how you feel using a simple 1-10 scale.
  • Set a daily reminder to consume your nutrition supplement at the same time each day (such as with breakfast). Log it immediately in the app to build consistency and track adherence over weeks and months.
  • Create a monthly summary dashboard showing total supplement days completed, average daily calories and protein, and subjective wellness ratings. Share this data with your healthcare provider during check-ups to assess whether supplements are working for you personally.

This article summarizes research findings and should not replace professional medical advice. Nutrition supplements are not appropriate for everyone and may interact with medications or health conditions. Before starting any nutrition supplement, consult with your doctor or registered dietitian, especially if you have kidney disease, diabetes, or take prescription medications. This review examined studies published 2014-2024 with most tracking results for 6 months or less; long-term safety and effectiveness require additional research. Individual results vary based on age, health status, and nutritional needs.

This research translation is published by Gram Research, the science division of Gram, an AI-powered nutrition tracking app.

Source: Systematic Review of Health Economic Evaluations of Oral Nutritional Supplement Interventions in Older Adults: An ISPOR Special Interest Group Report.Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research (2026). PubMed 42526758 | DOI